Can I get a disease (STI), including HIV, the first time I have vaginal or anal sex?

Yes, absolutely. There is no free pass for your first time, and all it takes to get infected is one time.

All sexually transmitted infections (stis) get passed through either skin-to-skin contact or the exchange of body fluids—and both of these things happen during vaginal and anal sex.

As far as HIV goes, vaginal and anal sex is the most common way of getting infected.

Therefore, you must remember to protect yourself and use a condom—even for your first time.